The house museum contains an artistic and literary legacy in line with the poet's era, and which the visitor can use as a guide for an interesting journey through the Spanish Golden Age. Although not every object in the house pertains to it or to other periods in the writer's life, it should be noted that each work of art, each book, and each piece of furniture has been carefully chosen to create a fitting collection for the objectives of the house: to pay tribute not only to Lope, but to the entire, rich Golden Age.

The existing heritage in the Lope de Vega house museum has numerous different sources: